“黑蛇”（乌玛?瑟曼 Uma Thurman 饰）继续上一集未完的复仇之旅
探听得知，前比尔的贴身保镖“响尾蛇”洗手不干后住在得克萨斯州的奥斯汀 当她晚上悄悄溜到“响尾蛇”住的拖车上时，却中了埋伏，被“响尾蛇”用枪击中胸部并被麻醉了
“响尾蛇”将“黑蛇”装到棺材里填埋 了 此时，“黑蛇”苏醒过来，运用她的师傅白眉老道所传授的功夫从棺材里脱身 当她回到“响尾蛇”所住的拖车时，发现“响尾蛇”和另一个追杀目标“加利福尼亚蛇”正在交易她随身携带的宝刀 打斗中，“加利福尼亚蛇”放出的巴曼蛇咬死了“响尾蛇”
“黑蛇”终于见到比尔了，并揭开了自己满门被杀的真相
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