故事开始于沪都大学303宿舍内，个性大大咧咧无畏惧他人眼光的林向宇（陈晓 饰），虽然身为海归富二代但心中只惦记着自己的宠物羊驼的李大鹏（杜天皓 饰），身强体壮但心思细腻温柔的谢训（李现 饰），拥有高超智商但缺少女人缘的学霸管超（刘芮麟 饰），这四位来自天南地北的大男孩们相聚在此，成为了朝夕相处的室友，拉开了有笑有泪的大学生活的序幕
短暂的四年一晃眼就要过去，站在人生的十字路口前，四人会做出怎样的选择 林向宇是否能够追求到他一直心系的“丝帕女生” 谢川和女友高宝镜（蓝盈莹 饰）之间的感情又会迎来怎样的结局呢
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